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Phase I/II study of R-CMOP for newly diagnosed bulky large B-cell lymphoma

ChiCTR2400093033Phase 4Recruiting

Sponsor
First Affiliated Hospital of Xi'an Jiaotong University
Start
Sep 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of rituximab, cyclophosphamide, mitoxantrone, vincristine and prednisone in diffuse large B-cell lymphoma (DLBCL) (2 arms), sponsored by First Affiliated Hospital of Xi'an Jiaotong University. Primary endpoints: Objective response rate in phase II and Recommended phase II dose of mitoxantrone hydrochloride liposome. Started Sep 2024; status: recruiting.

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Drugs

rituximabcyclophosphamidemitoxantronevincristineprednisone
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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