Trial intelligence / Profile preview

Cefiderocol versus colistin for carbapenem-resistant Gram-negative infections

ChiCTR2400094663Phase 3Recruiting

Sponsor
Huashan Hospital
Start
Dec 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of cefiderocol, colistimethate sodium and meropenem in hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), Healthcare-associated pneumonia (HCAP) and 4 more (2 arms), sponsored by Huashan Hospital. Primary endpoints: Clinical outcome at test of cure, Microbiological eradication at test of cure and 2 more. Started Dec 2024; status: recruiting.

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Drugs

cefiderocolcolistimethate sodiummeropenem
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Conditions

hospital-acquired pneumonia (HAP)ventilator-associated pneumonia (VAP)Healthcare-associated pneumonia (HCAP)Intra-abdominal infection (IAI)complicated urinary tract infection (cUTI)

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