Trial intelligence / Profile preview

Prospective Study on Neoadjuvant Treatments for Locally Advanced Rectal Cancer with Predicted TRG 3

ChiCTR2500096607Phase 4Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jan 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of oxaliplatin, fluorouracil, folinic acid and capecitabine in rectal cancer (2 arms), sponsored by West China Hospital of Sichuan University. Primary endpoints: Pathologic complete response (pCR) and Postoperative intestinal function score (LARS score). Planned start Jan 2025; status: not yet recruiting.

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Drugs

oxaliplatinfluorouracilfolinic acidcapecitabine
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Conditions

rectal cancer

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