Trial intelligence / Profile preview

Pharmacoeconomic analysis of tenofovir amibufenamide versus entecavir in chronic hepatitis B

ChiCTR2500097387Phase 4Completed

Sponsor
The First Affiliated Hospital of Wenzhou Medical University
Start
Feb 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label trial of tenofovir + amibufenamide and entecavir in Chronic Hepatitis B (CHB) (2 arms), sponsored by The First Affiliated Hospital of Wenzhou Medical University. Primary endpoint: HBV-DNA negative conversion rate at 48 weeks. Started Feb 2025; status: completed.

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Drugs

tenofovir + amibufenamideentecavir
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Conditions

Chronic Hepatitis B (CHB)

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