Trial intelligence / Profile preview

First-line irinotecan liposome + capecitabine + sintilimab with or without bevacizumab in RAS-mutant MSS metastatic colorectal cancer

ChiCTR2500097870Phase 2Not yet recruiting

Sponsor
Sichuan Cancer Hospital
Start
Feb 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of irinotecan liposome, capecitabine, sintilimab and bevacizumab in colorectal cancer (CRC), sponsored by Sichuan Cancer Hospital. Primary endpoints: Objective response rate and Adverse events. Planned start Feb 2025; status: not yet recruiting.

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Drugs

irinotecan liposomecapecitabinesintilimabbevacizumab
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Conditions

colorectal cancer (CRC)

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