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Zanubrutinib + chidamide + rituximab as first-line therapy in elderly patients with double-expressor DLBCL

ChiCTR2500098804Phase 2Recruiting

Sponsor
Fujian Medical University Union Hospital
Start
Mar 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of zanubrutinib, tucidinostat and rituximab in diffuse large B-cell lymphoma (DLBCL), sponsored by Fujian Medical University Union Hospital. Primary endpoint: 2-year progression-free survival. Started Mar 2025; status: recruiting.

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Drugs

zanubrutinibtucidinostatrituximab
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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