Trial intelligence / Profile preview

Trilaciclib plus envafolimab and EP chemotherapy versus envafolimab and EP in first-line extensive-stage small cell lung cancer

ChiCTR2500099059Phase 2Recruiting

Sponsor
Shanghai Chest Hospital
Start
Mar 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of trilaciclib, envafolimab, etoposide and carboplatin in small cell lung cancer (SCLC) (2 arms), sponsored by Shanghai Chest Hospital. Primary endpoint: Incidence of grade 3 or higher neutropenia. Started Mar 2025; status: recruiting.

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Drugs

trilaciclibenvafolimabetoposidecarboplatin
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Conditions

small cell lung cancer (SCLC)

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