Trial intelligence / Profile preview

Oliceridine vs sufentanil for postoperative analgesia in elderly knee arthroplasty

ChiCTR2500099271Phase 4Not yet recruiting

Sponsor
Shanghai Sixth People's Hospital
Start
Mar 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
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Overview

Phase 4, randomised trial in knee osteoarthritis (OA) and disorders of knee comparing TRV130 (oliceridine) PCA group with Sufentanil PCA group (2 arms). Primary endpoint: Difference in NRS time-weighted pain intensity scores at rest during the 48-hour treatment period. Planned start Mar 2025; status: not yet recruiting.

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Drugs

oliceridinesufentanil
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Conditions

knee osteoarthritis (OA)disorders of knee

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