Trial intelligence / Profile preview

Adebrelimab + disitamab vedotin + carboplatin versus nab-paclitaxel + carboplatin as neoadjuvant therapy for HER2-low breast cancer

ChiCTR2500100237Phase 2Recruiting

Sponsor
Sun Yat-sen Memorial Hospital
Start
Apr 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of adebrelimab, disitamab vedotin, carboplatin and paclitaxel in breast cancer (2 arms), sponsored by Sun Yat-sen Memorial Hospital. Primary endpoint: pathological response rate. Started Apr 2025; status: recruiting.

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Drugs

adebrelimabdisitamab vedotincarboplatinpaclitaxel
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Conditions

breast cancer

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