Trial intelligence / Profile preview

Phase II CKVD regimen in early-line relapsed or refractory multiple myeloma

ChiCTR2500100365Phase 2Not yet recruiting

Sponsor
Beijing Chaoyang Hospital
Start
Apr 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of aponermin, carfilzomib, venetoclax and dexamethasone in multiple myeloma (MM), sponsored by Beijing Chaoyang Hospital. Primary endpoint: Best complete response rate after CKVD treatment. Planned start Apr 2025; status: not yet recruiting.

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Drugs

aponermincarfilzomibvenetoclaxdexamethasone
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Conditions

multiple myeloma (MM)

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