Trial intelligence / Profile preview

Iparomlimab + tuvonralimab with neoadjuvant carboplatin/paclitaxel for newly diagnosed advanced epithelial ovarian cancer

ChiCTR2500101134Phase 2Not yet recruiting

Sponsor
Sichuan Cancer Hospital
Start
Apr 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of iparomlimab, tuvonralimab, paclitaxel and carboplatin in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC), sponsored by Sichuan Cancer Hospital. Primary endpoint: Pathological complete response. Planned start Apr 2025; status: not yet recruiting.

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Drugs

iparomlimabtuvonralimabpaclitaxelcarboplatin
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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