Trial intelligence / Profile preview

DEC3-VEN-HHT for newly diagnosed core-binding factor or RUNX1::RUNX1T1 acute myeloid leukemia

ChiCTR2500101192Phase 2Recruiting

Sponsor
Tai'an City Central Hospital
Start
Apr 2025
Modality
Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of venetoclax, decitabine and homoharringtonine in acute myeloid leukemia (AML), sponsored by Tai'an City Central Hospital. Primary endpoints: Complete remission rate and Complete remission with incomplete hematologic recovery. Started Apr 2025; status: recruiting.

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Drugs

venetoclaxdecitabinehomoharringtonine
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Conditions

acute myeloid leukemia (AML)

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