Trial intelligence / Profile preview

Aponermin plus CyBorD in newly diagnosed systemic light chain amyloidosis

ChiCTR2500102256Phase 4Not yet recruiting

Sponsor
Tianjin Medical University General Hospital
Start
May 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of aponermin, cyclophosphamide, bortezomib and dexamethasone in light-chain amyloidosis, sponsored by Tianjin Medical University General Hospital. Primary endpoint: Overall response rate. Planned start May 2025; status: not yet recruiting.

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Drugs

aponermincyclophosphamidebortezomibdexamethasone
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Conditions

light-chain amyloidosis

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