Trial intelligence / Profile preview

BL-B01D1 plus almonertinib as neoadjuvant therapy followed by adjuvant almonertinib in resectable EGFR-mutant non-small cell lung cancer

ChiCTR2500102344Phase 2Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
May 2025
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of izalontamab brengitecan and almonertinib in non-small cell lung cancer (NSCLC), sponsored by West China Hospital of Sichuan University. Primary endpoints: pathological complete response and major pathological response. Planned start May 2025; status: not yet recruiting.

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Drugs

izalontamab brengitecanalmonertinib
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Conditions

non-small cell lung cancer (NSCLC)

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