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FTD/TPI + regorafenib vs FTD/TPI + bevacizumab in refractory metastatic colorectal cancer

ChiCTR2500102445Phase 4Not yet recruiting

Sponsor
Second Affiliated Hospital of Zhejiang University School of Medicine
Start
Jun 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in colorectal adenocarcinoma comparing Trifluridine-tipiracil + bevacizumab with Trifluridine-tipiracil + regorafenib (2 arms). Primary endpoint: Progression-free survival. Planned start Jun 2025; status: not yet recruiting.

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Drugs

trifluridine + tipiracilregorafenibbevacizumab
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Conditions

colorectal adenocarcinoma

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