Trial intelligence / Profile preview

Iparomlimab and Tuvonralimab plus chemotherapy and bevacizumab for advanced melanoma

ChiCTR2500103154Phase 2Not yet recruiting

Sponsor
Shanghai Tenth People's Hospital
Start
May 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of iparomlimab, tuvonralimab, paclitaxel, carboplatin and bevacizumab in melanoma, sponsored by Shanghai Tenth People's Hospital. Primary endpoint: Objective response rate. Planned start May 2025; status: not yet recruiting.

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Drugs

iparomlimabtuvonralimabpaclitaxelcarboplatinbevacizumab
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Conditions

melanoma

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