Trial intelligence / Profile preview

SKB264 plus pembrolizumab neoadjuvant phase II trial in triple-negative breast cancer

ChiCTR2500103244Phase 2Not yet recruiting

Sponsor
Yantai Yuhuangding Hospital
Start
May 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sacituzumab tirumotecan and pembrolizumab in triple-negative breast cancer (TNBC), sponsored by Yantai Yuhuangding Hospital. Primary endpoint: Pathological complete response rate. Planned start May 2025; status: not yet recruiting.

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Drugs

sacituzumab tirumotecanpembrolizumab
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Conditions

triple-negative breast cancer (TNBC)

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