Trial intelligence / Profile preview

AVL combination therapy in newly diagnosed elderly AML/MDS

ChiCTR2500103716Phase 2Not yet recruiting

Sponsor
Army Medical Center of PLA
Start
Jun 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of azacitidine, venetoclax and lenalidomide in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), sponsored by Army Medical Center of PLA. Primary endpoint: Objective response rate. Planned start Jun 2025; status: not yet recruiting.

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Drugs

azacitidinevenetoclaxlenalidomide
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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