Trial intelligence / Profile preview

Subanesthetic esketamine for perioperative neurocognitive disorders in metabolic syndrome patients undergoing major abdominal surgery

ChiCTR2500104082Phase 4Completed

Sponsor
Yantai Yuhuangding Hospital
Start
Jun 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial of esketamine in perioperative neurocognitive disorder, post-operative cognitive decline (POCD) and postoperative delirium (POD) (2 arms), sponsored by Yantai Yuhuangding Hospital. Primary endpoints: Incidence of delayed neurocognitive recovery, Mini-Mental State Examination score and 1 more. Started Jun 2025; status: completed.

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Drugs

esketamine
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Conditions

perioperative neurocognitive disorderpost-operative cognitive decline (POCD)postoperative delirium (POD)

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