Trial intelligence / Profile preview

Iparomlimab + Tuvorralimab with neoadjuvant chemotherapy for resectable thoracic esophageal squamous cell carcinoma

ChiCTR2500104210Phase 2Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jun 2025
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of iparomlimab, ambuzutinib, paclitaxel and cisplatin in Esophageal Squamous Cell Carcinoma (ESCC), sponsored by West China Hospital of Sichuan University. Primary endpoint: Pathological complete remission rate. Planned start Jun 2025; status: not yet recruiting.

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Drugs

iparomlimabambuzutinibpaclitaxelcisplatin
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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