Trial intelligence / Profile preview

Luspatercept plus azacitidine in intermediate- and high-risk myelodysplastic syndromes

ChiCTR2500104329Phase 2Recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jun 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of luspatercept and azacitidine in myelodysplastic syndrome (MDS), sponsored by West China Hospital of Sichuan University. Primary endpoints: Complete remission rate in bone marrow and Red blood cell transfusion independence ≥ 8 weeks. Started Jun 2025; status: recruiting.

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Drugs

luspaterceptazacitidine
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Conditions

myelodysplastic syndrome (MDS)

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