Trial intelligence / Profile preview

Phase II ZR-MTX trial for primary intraocular lymphoma

ChiCTR2500104446Phase 2Recruiting

Sponsor
Peking Union Medical College Hospital
Start
Jun 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of rituximab, zanubrutinib and methotrexate in primary intraocular lymphoma (PIOL), sponsored by Peking Union Medical College Hospital. Primary endpoint: Progression-free survival. Started Jun 2025; status: recruiting.

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Drugs

rituximabzanubrutinibmethotrexate
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Conditions

primary intraocular lymphoma (PIOL)

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