Trial intelligence / Profile preview

AZD9829 in CD123-positive hematological malignancies

ChiCTR2500104541Phase 2Recruiting

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
Jun 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of AZD9829 in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoints: Incidence of dose-limiting toxicities (DLTs), Incidence, severity, and relationship to AZD9829 of adverse events (AEs) and serious adverse events (SAEs) and 4 more. Started Jun 2025; status: recruiting.

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Drugs

AZD9829
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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