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Utidelone + S-1 + anlotinib + sintilimab for first-line HER2-negative advanced gastric/GEJ adenocarcinoma

ChiCTR2500104634Phase 2Not yet recruiting

Sponsor
Shanghai Changzheng Hospital
Start
Jun 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of utidelone, tegafur, anlotinib and sintilimab in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, sponsored by Shanghai Changzheng Hospital. Primary endpoint: Objective response rate. Planned start Jun 2025; status: not yet recruiting.

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Drugs

utidelonetegafuranlotinibsintilimab
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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