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Opioid-free anesthesia with lidocaine + esketamine vs traditional opioid anesthesia in children
ChiCTR2500105161Phase 4Not yet recruiting
- Sponsor
- The First College of Clinical Medical Science, China Three Gorges University
- Start
- Jun 2025
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised trial of lidocaine, esketamine, sufentanil, tramadol and ibuprofen in postoperative respiratory complications (PRC), postoperative pain, postoperative delirium (POD) and 1 more (2 arms), sponsored by The First College of Clinical Medical Science, China Three Gorges University. Primary endpoint: Perioperative adverse respiratory events (PRAE). Planned start Jun 2025; status: not yet recruiting.
02
Drugs
lidocaineesketaminesufentaniltramadolibuprofen
03
Conditions
postoperative respiratory complications (PRC)postoperative painpostoperative delirium (POD)preoperative anxiety
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