Trial intelligence / Profile preview

SGLT2 inhibitor plus GLP-1 receptor agonist for cardiorenal metabolic syndrome

ChiCTR2500105669Phase 4Recruiting

Sponsor
Zhongshan Hospital, Fudan University
Start
Jul 2025
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of dulaglutide, exenatide, liraglutide, semaglutide, canagliflozin and 2 more in cardiovascular-kidney-metabolic syndrome, cardiac morbidity, chronic kidney disease (CKD) and 1 more (3 arms), sponsored by Zhongshan Hospital, Fudan University. Primary endpoints: Major cardiovascular events (MACE) and Renal events. Started Jul 2025; status: recruiting.

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Drugs

dulaglutideexenatideliraglutidesemaglutidecanagliflozin
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Conditions

cardiovascular-kidney-metabolic syndromecardiac morbiditychronic kidney disease (CKD)type 2 diabetes mellitus (T2DM)

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