Trial intelligence / Profile preview

HAIC FOLFOX + tislelizumab + lenvatinib as neoadjuvant therapy for resectable high‑risk recurrent hepatocellular carcinoma

ChiCTR2500106287Phase 4Not yet recruiting

Sponsor
Second Affiliated Hospital of Zhejiang University School of Medicine
Start
Jul 2025
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of tislelizumab, lenvatinib, oxaliplatin, folinic acid and fluorouracil in hepatocellular carcinoma (HCC), sponsored by Second Affiliated Hospital of Zhejiang University School of Medicine. Primary endpoint: 1-year recurrence-free survival rate. Planned start Jul 2025; status: not yet recruiting.

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Drugs

tislelizumablenvatiniboxaliplatinfolinic acidfluorouracil
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Conditions

hepatocellular carcinoma (HCC)

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