Trial intelligence / Profile preview

Neoadjuvant cadonilimab vs sintilimab plus perioperative SOX in diffuse locally advanced gastric/GEJ adenocarcinoma

ChiCTR2500106399Phase 3Not yet recruiting

Sponsor
Second Hospital of Lanzhou University
Start
Sep 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma comparing Cadonilimab + SOX with Sintilimab + SOX (2 arms). Primary endpoints: Pathological complete response rate and Median disease-free survival. Planned start Sep 2025; status: not yet recruiting.

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Drugs

cadonilimabsintilimab
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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