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Nocturnal Hypertension Control in HFpEF: Sacubitril/valsartan With or Without Dapagliflozin

ChiCTR2500106491Phase 4Recruiting

Sponsor
Third People's Hospital of Chengdu
Start
Aug 2023
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised trial in heart failure with preserved ejection fraction (HFpEF), nocturnal hypertension (NH) and hypertension (HTN) comparing Sacubitril/valsartan monotherapy with Sacubitril/valsartan plus dapagliflozin (2 arms). Primary endpoints: All-cause death or cardiovascular death and Heart failure rehospitalization. Started Aug 2023; status: recruiting.

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Drugs

sacubitril + valsartandapagliflozin
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Conditions

heart failure with preserved ejection fraction (HFpEF)nocturnal hypertension (NH)hypertension (HTN)

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