Trial intelligence / Profile preview

Firmonertinib + anlotinib first-line therapy for EGFR-mutant NSCLC with brain metastases

ChiCTR2500106565Phase 2Recruiting

Sponsor
Henan Cancer Hospital
Start
Jul 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of furmonertinib and anlotinib in non-small cell lung cancer (NSCLC) and brain metastases, sponsored by Henan Cancer Hospital. Primary endpoints: Safety (Phase I: safety lead-in) and Progression-Free Survival (PFS) (Phase II: formal study). Started Jul 2025; status: recruiting.

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Drugs

furmonertinibanlotinib
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Conditions

non-small cell lung cancer (NSCLC)brain metastases

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