Trial intelligence / Profile preview

ZSDT regimen for BTK inhibitor–refractory mantle cell lymphoma

ChiCTR2500106604Phase 4Not yet recruiting

Sponsor
The First Affiliated Hospital of Zhengzhou University
Start
Jul 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, IgG Antibodies → Naked Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
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Overview

Phase 4, open-label, single-arm trial of hlx01, selinexor, dexamethasone and thalidomide in mantle cell lymphoma (MCL), sponsored by The First Affiliated Hospital of Zhengzhou University. Primary endpoint: Complete response rate. Planned start Jul 2025; status: not yet recruiting.

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Drugs

hlx01selinexordexamethasonethalidomide
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Conditions

mantle cell lymphoma (MCL)

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