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Perioperative esketamine for pain catastrophizing and chronic postsurgical pain after traumatic lower limb fractures

ChiCTR2500106619Phase 4Not yet recruiting

Sponsor
Tongling People's Hospital
Start
Jul 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised trial of esketamine in Persistent postsurgical pain (PPSP), acute postoperative pain, Pain catastrophizing (PC) and 2 more (2 arms), sponsored by Tongling People's Hospital. Primary endpoint: Chronic postsurgical pain. Planned start Jul 2025; status: not yet recruiting.

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Drugs

esketamine
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Conditions

Persistent postsurgical pain (PPSP)acute postoperative painPain catastrophizing (PC)anxiety disordermajor depressive disorder (MDD)

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