Trial intelligence / Profile preview

Neratinib extended intensive therapy after adjuvant anti-HER2 treatment in high-risk early or locally advanced HER2-positive breast cancer

ChiCTR2500107226Phase 4Not yet recruiting

Sponsor
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Start
Aug 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of neratinib in breast cancer, sponsored by Shandong Provincial Hospital Affiliated to Shandong First Medical University. Primary endpoint: Invasive disease-free survival. Planned start Aug 2025; status: not yet recruiting.

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Drugs

neratinib
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Conditions

breast cancer

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