Trial intelligence / Profile preview

Real-world Polatuzumab Vedotin in aggressive B-cell NHL (China)

ChiCTR2500107582Phase 4Recruiting

Sponsor
Henan Cancer Hospital
Start
Aug 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, open-label trial of polatuzumab vedotin in non-Hodgkin lymphoma (NHL), diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma (PMBCL) and 6 more (2 arms), sponsored by Henan Cancer Hospital. Primary endpoint: Objective Response Rate. Started Aug 2025; status: recruiting.

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Drugs

polatuzumab vedotin
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Conditions

non-Hodgkin lymphoma (NHL)diffuse large B-cell lymphoma (DLBCL)primary mediastinal large B-cell lymphoma (PMBCL)primary central nervous system lymphoma (PCNSL)follicular lymphoma (FL)

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