Trial intelligence / Profile preview

Phase III Study of PLB1004 in EGFR Exon 20 Insertion Mutant NSCLC

ChiCTR2500107929Phase 3Recruiting

Sponsor
Guangdong Provincial People's Hospital
Start
Aug 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of andamertinib in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Guangdong Provincial People's Hospital. Primary endpoint: Progression-free survival (PFS) by BICR. Started Aug 2025; status: recruiting.

02

Drugs

andamertinib
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Conditions

non-small cell lung cancer (NSCLC)

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