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Metformin + hengglizin vs metformin in type 2 diabetes with metabolic fatty liver disease

ChiCTR2500108637Phase 4Recruiting

Sponsor
Foshan First People's Hospital
Start
Sep 2025
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of metformin in type 2 diabetes mellitus (T2DM), Metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic fatty pancreatic disease (NAFPD) (3 arms), sponsored by Foshan First People's Hospital. Primary endpoints: Liver fat content at 52 weeks, Pancreatic fat content at 52 weeks and 1 more. Started Sep 2025; status: recruiting.

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Drugs

metformin
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Conditions

type 2 diabetes mellitus (T2DM)Metabolic dysfunction-associated fatty liver disease (MAFLD)non-alcoholic fatty pancreatic disease (NAFPD)

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