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Oliceridine + ondansetron vs sufentanil + ondansetron for prevention of postoperative nausea and vomiting and QTc safety in hysteroscopic surgery

ChiCTR2500109721Phase 4Not yet recruiting

Sponsor
Wang Chenggang(Study sponsor)
Start
Sep 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised trial in postoperative nausea and vomiting (PONV) comparing O group: oliceridine + ondansetron with S group: sufentanil + ondansetron (2 arms). Primary endpoints: Incidence of nausea and vomiting within 24 hours postoperatively and QTc interval variation. Planned start Sep 2025; status: not yet recruiting.

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Drugs

oliceridineondansetronsufentanil
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Conditions

postoperative nausea and vomiting (PONV)

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