Trial intelligence / Profile preview

Sequential CCRT plus surgery vs surgery alone in non-CCR ESCC after neoadjuvant chemoimmunotherapy

ChiCTR2500109910Phase 3Not yet recruiting

Sponsor
Sichuan Cancer Hospital
Start
Sep 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of tislelizumab, paclitaxel and carboplatin in Esophageal Squamous Cell Carcinoma (ESCC) (2 arms), sponsored by Sichuan Cancer Hospital. Primary endpoint: Pathological complete response rate (pCR). Planned start Sep 2025; status: not yet recruiting.

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Drugs

tislelizumabpaclitaxelcarboplatin
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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