Trial intelligence / Profile preview

Thalidomide + TGA vs TGA in relapsed/refractory extracranial germ cell tumors in children and adolescents

ChiCTR2500110311Phase 2Not yet recruiting

Sponsor
Shandong Cancer Hospital
Start
Oct 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of thalidomide, paclitaxel, gemcitabine and epirubicin in germ cell tumor (GCT) (2 arms), sponsored by Shandong Cancer Hospital. Primary endpoint: Objective response rate (ORR). Planned start Oct 2025; status: not yet recruiting.

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Drugs

thalidomidepaclitaxelgemcitabineepirubicin
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Conditions

germ cell tumor (GCT)

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