Trial intelligence / Profile preview

Bcl-2 inhibitor plus blinatumomab induction vs pediatric-inspired chemotherapy in adult Ph-negative ALL

ChiCTR2500111430Phase 2Not yet recruiting

Sponsor
Xinqiao Hospital
Start
Oct 2025
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of blinatumomab in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by Xinqiao Hospital. Primary endpoint: The rate of minimal residual disease negativity (flow cytometry). Planned start Oct 2025; status: not yet recruiting.

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Drugs

blinatumomab
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Conditions

acute lymphoblastic leukemia (ALL)

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