Trial intelligence / Profile preview

Sacituzumab Tirumotecan in Second-Line or Later Advanced Biliary Tract Cancer (Single-Arm Phase II)

ChiCTR2500112219Phase 2Not yet recruiting

Sponsor
The First Affiliated Hospital of Zhengzhou University
Start
Nov 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sacituzumab tirumotecan in biliary cancer, intrahepatic cholangiocarcinoma (ICC), cholangiocarcinoma (CCA) and 1 more, sponsored by The First Affiliated Hospital of Zhengzhou University. Primary endpoint: Progression-free survival (PFS). Planned start Nov 2025; status: not yet recruiting.

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Drugs

sacituzumab tirumotecan
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Conditions

biliary cancerintrahepatic cholangiocarcinoma (ICC)cholangiocarcinoma (CCA)gallbladder cancer

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