Trial intelligence / Profile preview

Phase II/III SYS6010 + SG001 ± chemotherapy in advanced esophageal squamous cell carcinoma

ChiCTR2500112440Phase 3Not yet recruiting

Sponsor
Sun Yat-sen University Cancer Center
Start
Nov 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised trial of CPO301, PBI-1308, camrelizumab and tislelizumab in Esophageal Squamous Cell Carcinoma (ESCC) (13 arms), sponsored by Sun Yat-sen University Cancer Center. Primary endpoints: Incidence of Dose-Limiting Toxicities (DLTs), Adverse Events (AEs) and 5 more. Planned start Nov 2025; status: not yet recruiting.

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Drugs

CPO301PBI-1308camrelizumabtislelizumab
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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