Trial intelligence / Profile preview

Neoadjuvant Disitamab Vedotin + Chemotherapy ± PD-1 in HER2-low Gastric/GEJ Adenocarcinoma

ChiCTR2500112528Phase 2Not yet recruiting

Sponsor
Sun Yat-sen University Cancer Center
Start
Nov 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of disitamab vedotin in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Sun Yat-sen University Cancer Center. Primary endpoint: Tumor Regression Grade 0/1 (TRG 0/1). Planned start Nov 2025; status: not yet recruiting.

02

Drugs

disitamab vedotin
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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