Trial intelligence / Profile preview

Fruquintinib + TAS-102 second-line maintenance in metastatic colorectal cancer

ChiCTR2500112655Phase 4Not yet recruiting

Sponsor
Anhui Provincial Tumor Hospital
Start
Nov 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of fruquintinib and trifluridine + tipiracil in colorectal cancer (CRC) (2 arms), sponsored by Anhui Provincial Tumor Hospital. Primary endpoint: Progression-free survival (PFS). Planned start Nov 2025; status: not yet recruiting.

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Drugs

fruquintinibtrifluridine + tipiracil
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Conditions

colorectal cancer (CRC)

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