Trial intelligence / Profile preview

SHR-A1811 + QL1706 as first-line therapy for HER2-overexpressing NSCLC

ChiCTR2500114106Phase 2Not yet recruiting

Sponsor
Shanghai Pulmonary Hospital
Start
Dec 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab rezetecan and QL1706 in non-small cell lung cancer (NSCLC), sponsored by Shanghai Pulmonary Hospital. Primary endpoint: 12-month Progression-Free Survival Rate. Planned start Dec 2025; status: not yet recruiting.

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Drugs

trastuzumab rezetecanQL1706
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Conditions

non-small cell lung cancer (NSCLC)

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