Trial intelligence / Profile preview

Inclisiran for Prevention of Postoperative Complications After Off-pump CABG

ChiCTR2500114213Phase 4Not yet recruiting

Sponsor
Jiangsu Provincial People's Hospital
Start
Dec 2025
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
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Overview

Phase 4, randomised trial of inclisiran in coronary arteriosclerosis (2 arms), sponsored by Jiangsu Provincial People's Hospital. Primary endpoints: Incidence of adverse cardiovascular and cerebrovascular events within three months and 3-month graft patency rate. Planned start Dec 2025; status: not yet recruiting.

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Drugs

inclisiran
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Conditions

coronary arteriosclerosis

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