Trial intelligence / Profile preview

ZG005 + gilteritinib in relapsed or refractory lymphoma (phase I/II)

ChiCTR2500114728Phase 2Recruiting

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Dec 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of nilvanstomig and gilteritinib in classical Hodgkin lymphoma (cHL), primary mediastinal large B-cell lymphoma (PMBCL), Extranodal natural killer/T-cell lymphoma, nasal type (ENKTL) and 1 more (3 arms), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoints: Objective response rate (ORR) by LYRIC criteria and Safety. Started Dec 2025; status: recruiting.

02

Drugs

nilvanstomiggilteritinib
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Conditions

classical Hodgkin lymphoma (cHL)primary mediastinal large B-cell lymphoma (PMBCL)Extranodal natural killer/T-cell lymphoma, nasal type (ENKTL)lymphoma

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