Trial intelligence / Profile preview

Neoadjuvant pembrolizumab + platinum + taxane in HPV-negative locally advanced head and neck squamous cell carcinoma

ChiCTR2500114853Phase 2Recruiting

Sponsor
Sun Yat-sen University Cancer Center
Start
Dec 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
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Overview

Phase 2, open-label, single-arm trial of pembrolizumab in head and neck squamous cell carcinoma (HNSCC), sponsored by Sun Yat-sen University Cancer Center. Primary endpoint: Pathological complete response rate (pCR). Started Dec 2025; status: recruiting.

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Drugs

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Conditions

head and neck squamous cell carcinoma (HNSCC)

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