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Liposomal bupivacaine vs ropivacaine paravertebral block for postoperative psychological symptoms after thoracoscopic surgery

ChiCTR2500114947Phase 4Not yet recruiting

Sponsor
Qingdao Municipal Hospital
Start
Dec 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
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Overview

Phase 4, randomised, double-blind trial in anxiety disorder, postoperative depression, None and 2 more comparing Ropivacaine paravertebral nerve block with Liposomal bupivacaine paravertebral nerve block (2 arms). Primary endpoint: Postoperative psychological symptoms (anxiety, depression, stress, sleep). Planned start Dec 2025; status: not yet recruiting.

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Drugs

bupivacaineropivacaine
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Conditions

anxiety disorderpostoperative depressionsleep disorderpostoperative pain

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