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OR2 regimen (orelabrutinib + rituximab + lenalidomide) in untreated marginal zone lymphoma

ChiCTR2500115204Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Dec 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of orelabrutinib, rituximab and lenalidomide in marginal zone B-cell lymphoma (MZL), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoint: Overall response rate. Planned start Dec 2025; status: not yet recruiting.

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Drugs

orelabrutinibrituximablenalidomide
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Conditions

marginal zone B-cell lymphoma (MZL)

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